Longitudinal age-dependent effect on systolic blood pressure

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Longitudinal age-dependent effect on systolic blood pressure

Age-dependent genetic effects on susceptibility to hypertension have been documented. We present a novel variance-component method for the estimation of age-dependent genetic effects on longitudinal systolic blood pressure using 57,827 Affymetrix single-nucleotide polymorphisms (SNPs) on chromosomes 17-22 genotyped in 2,475 members of the Offspring Cohort of the Framingham Heart Study. We used ...

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The Effect of Chronic Administration of Safranal on Systolic Blood Pressure in Rats

Safranal, the main component of Crocus sativus essential oil, exhibits different pharmacological activities. In this study, the effects of safranal, on blood pressure of normotensive and desoxycorticosterone acetate (DOCA) - salt induced hypertensive rats in chronic administration were investigated. Three doses of safranal (1, 2 and 4 mg/kg/day) and spironolactone (50 mg/kg/day) were administra...

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Effect of age on blood pressure and membrane-dependent vascular responses in the rat.

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ژورنال

عنوان ژورنال: BMC Proceedings

سال: 2009

ISSN: 1753-6561

DOI: 10.1186/1753-6561-3-s7-s87